About Alkemy Innovation


Alkemy Innovation Inc. is an engineering company, founded on the premise that there is a new opportunity to rethink the approach to process development in the life sciences and pharmaceutical markets. 

We work with clients to identify opportunities to implement solutions that will ultimately drive innovation and growth while reducing costs.

With a well-developed acumen in crafting process analytical technology (PAT) and data analytics solutions for the pharmaceutical, life science and related industries, we leverage a number of available technologies and tools that support optimal data management, analytics, visualization, and reporting:

  • Company Focus: Scale-up/tech transfer strategies, data analytics, process modeling, batch and continuous processing innovations, Process Analytical Technology (PAT) solutions. 
  • Providing:
    • Consulting Services: Delivering scientific expertise to support the advancement of patient-focused therapies
    • Products: Providing the Biotech Lab Module to support effective data analytics and knowledge-sharing
  • Expertise:
    • Pharmaceutical Process Development:  Technology Selection and Implementation
    • Product Development: Reduction to Practice and Scale-up (Lab through Commercial Scale)
    • Engineering and Process Modeling
    • Process Analytical Technology (PAT) Assessments and Successful Implementation
    • How to Effectively Couple Automated Sampling, PAT, and Data Analytics Solutions for Complete Process Understanding
  • Striving to:
    • Deliver Value that has Lasting, Positive Impact
    • Apply Cross-Industry Learnings to Bring Products to Market
    • Create Long-Term, Collaborative Partnerships
  • Collaboration:  Alkemy Innovation Inc. values developing solutions collaboratively with groups of industry leaders so that a solution can be broadly adopted in advancing new products and medicines. 

  • Partnerships: The company also values creating partnerships with companies who want to tailor their hardware and software solutions to the scientists and engineers who run the R&D, pilot, and manufacturing scale processes.

Examples of Offerings Include:

  • Technical and business-focused consulting support for strategic plan development. Specific examples:
    • Sample and data management, upstream and downstream.
    • Continuous manufacturing opportunities.
    • On-line measurements combined with at-line analysis (and on-line).
    • Correlation of product quality to key process variables.
    • Model-based, predictive, process control options.
    • Automation of repeated analysis tasks and reporting for future reference.
  • Hardware and software technology assessment (including process analytical technologies) and implementation.
  • Data-driven model development and seamless integration into workflow. Includes first principles-based model development and approaches to identify key relationships.
  • Data analysis, data visualization, and data reporting strategy development.
  • Software development planning and execution.

Technical Resources:

  • "Of Microbrews and Medicines: Understanding Their Similarities and Differences in Bioprocessing Can Help Improve Yields and Quality While Reducing Cost", L. J. Graham, Bioprocess International, February 2018. (Link)

  • "Implementing a Culture-Driven Data Analytics Approach to Support Tech Transfer and Product Launch", L. J. Graham, Published in Pharmaceutical Processing, November 2017. (Link)

  • "Creating Value from Data Assets", L. J. Graham, Published in Pharmaceutical Manufacturing, September 2017. (Link)

  • "Deriving Insight at the Speed of Thought: Advancing Medicine Production Through an Effective Data Analytics Methodology", L. J. Graham, Published in BioProcessing Journal, May 2016. (Link)

  • "Leveraging Data Analytics Innovations to Improve Process Outcomes",  L. J. Graham, Published in Biopharm International, November 2016. (Link)

  • "Automating Online Sampling of Bioprocesses", C. A. Challener, Published in Pharmaceutical Technology, Vol 38, Issue 7, July 2014. (Link)

  • "A Novel Approach for Using Dielectric Spectroscopy to Predict Viable Cell Volume (VCV) in Early Process Development", B. J. Downey, L. J. Graham, J. F. Breit, and N. K. Glutting, Published in Biotechnology Progress, March 2014. (Link)

  • "Sterile, Automated Sampling Enabling PAT for Biopharmaceutical Manufacturing", Published in Pharmaceutical Technology, October 2013. (Link)

  • "Data Integration Methodology that Couples Novel Bioreactor Monitoring Tools; Automated Sampling and Applied Mathematics to Redefine Bioproduction Processes", L. J. Graham et al, Presented at the  23rd European Society for Animal Cell Technology (ESACT) Meeting: Better Cells for Better Health, Lille, France. 23-26 June 2013. (Link)

  • "Insights into Monitoring Changes in the Viable Cell Density and Cell Physiology Using Scanning, Multi-Frequency Dielectric Spectroscopy", J. Carvell, L.J. Graham, and B. Downey., Presented at the 23rd European Society for Animal Cell Technology (ESACT) Meeting: Better Cells for Better Health Lille, France. 23-26 June 2013. (Link)


About the Founder

Lisa Graham   Lisa J. Graham is a registered professional chemical engineer (Ph.D.) with 20 years experience across many industries: pharmaceuticals and life sciences (15 years), specialty and commodity chemicals, agriculture, pulp and paper, and wafer manufacturing for electronics. Her technical strengths include: Chemical engineering expertise, product development expertise, process model development, technology assessments of process analytical technologies, applied mathematics/data models, and creating hardware and software solutions for gathering better data and enabling streamlined data analysis/data visualization.

She has had the opportunity to develop a strong business background through C-Level leadership positions, including COO and SVP roles at Bend Research (now Lonza), and co-founding Black Canyon Woodworks in Bend, Oregon. She is actively involved in supporting higher education, specific STEM education initiatives, and economic development at the State and National level. Specific efforts include serving as Director on the Oregon Governor's STEM Investment Council (Since 2013) and as Chair of the Oregon Board of Trustees for Oregon Tech University (OIT) (Since 2014). (*STEM: Science, Technology, Engineering, Math)

Education/Professional Licensing

  • Ph.D., Chemical Engineering Oregon State University, 1999. 
  • B.S., Chemical Engineering, Oregon State University, 1995.
  • Registered Professional Engineer (53802PE) Oregon, Since 2008.


  • Oregon State University's Academy of Distinguished Engineers - 2016 (Link)

Lisa Graham is a business leader who speaks science. The technical foundation Graham established at Oregon State gave her the skill set necessary to adapt research and development methodologies to diverse industries, including pharmaceuticals, chemical processing, wafer manufacturing, and agriculture. As her career progressed, she supplemented her technical expertise with business development, technology development, strategic planning, financial planning, operations management, and other leadership skills. After working as a senior engineer at Union Carbide, she moved into the pharmaceutical sector at Bend Research in 2002, eventually becoming a senior vice president. In 2014, she moved to Paradigm as chief scientist, where she was responsible for the growth of technology areas focused on data/systems analysis, sensor technology, software development, and unmanned aerial vehicles in agriculture. Most recently, Graham founded Alkemy Innovation, a company that will enable rapid data analytics and model development for scientists in numerous industries. “Here’s a challenge right now with big data, and an emphasis on being able to access that data and gain useful knowledge from it,” she said. “My company will develop science-based software solutions that provide specific technical guidance relevant to each industry.” Graham has a strong passion for STEM education. “I didn’t get here on my own,” she said. “People have taken time they didn’t have to open doors for me.” In that spirit, she serves as chair of Oregon Tech University’s governing board, a director on the Oregon governor’s STEM Investment Council, and member of the College of Engineering’s School of Chemical, Biological, and Environ- mental Engineering’s advisory board. More...

  • Oregon State University's Council of Outstanding Early Career Engineers - 2010 (Link)

Dr. Lisa J. Graham earned a BS in Chemical Engineering from Oregon State University in 1995 and in 1999 completed her PhD. Dr. Graham joined Union Carbide, a Subsidiary of the Dow Chemical Company as Senior Engineer in a supervisory role. Lisa received recognition awards for technical achievement and leadership from Union Carbide and Dow. In 2002, Dr. Graham began work with Bend Research, Inc. Starting out as a research chemical engineer, Lisa quickly moved up to Vice President of Engineering in 2008 and in 2009 became Chief Operating Officer.



  • Systems and Methods for Producing Bioproducts, Issued Feb. 5, 2013  (PCT/US2012/061706; WO/2013/063128) (Link)

  • Dielectric Spectroscopy Methods and Apparatus  Issued Nov. 7, 2013 2017 (PCT/US2013/020397; WO/2013/103901) (Link)


More on LinkedIN - Here


Responsibility: Providing Support for the Arts and STEM

Alkemy Innovation Inc. also values active support for education of the combined fields of Arts and STEM (Science, Technology, Engineering, Mathematics).

“The difference between science and the arts is not that they are different sides of the same coin… or even different parts of the same continuum, but rather, they are manifestations of the same thing. The arts and sciences are avatars of human creativity.”

~ Mae Jemison, a doctor, dancer and first African American woman in space.


      For example,

  • An education rich in the arts will help kids excel in math and science

  • Art is not a charity, but rather an integral piece of a successful business strategy

  • STEM creates a powerful synergy between art and technological advancements

  • Business and communities can find ways to volunteer, fund and politically support Arts and STEM

Lisa Graham Washington D.C. STEM White House
Photo:  Lisa Graham, CEO and Founder, at the STEM Ecosystems Community of Practice Kickoff Meeting at the White House, Washington D.C., November 11-12, 2015.
More at http://stemecosystems.org/community-of-practice/

A few examples of our Arts and STEM community involvement!


From Data to Direction.

Contact Info

Alkemy Innovation
541-408- 4175
Bend, OR